Conversion factor
Posted: Mon Feb 25, 2008 6:50 pm
I have free base as standard and hydrochloride salt as my sample...How I should calculate my % recovery..what will be the conversion factors..how to calculate that..thanks in advance
factor =MW of salt/Mw of free base, this will produce a factor >1
Multiply your results by this factor to obtain the salt concentration from the measured free base concentration.
or (preferably)
Convert you STD concs to equivalent salt concs (factor =MW of free base/Mw of salt, this will produce a factor <1), by multiplying the free base conc by the factor.
Tip: if you do the adjustment at the Stock STD prep, you only need to do one calculation (calculate all other STD concs as normal from the "adjusted" Stock STD conc)