Chromatography Forum

I want to detect 2-chloroethanol, by GC/FID. Which column is suitable for this?????????

That depends on what else is in the sample.

Peter

I did find a reference to DB-1/OV-1 type phase where it elutes around C6. However, Peter is right in that it is not just a function of getting it off the column but really separting it from the other things coming off the column.

This might be tough at trace levels with FID since it has low carbon count, and an oxygen and chlorine all on one molecule. Did you want trace?

Best regards.

A non-reactive moderate polarity column would be the best choice.

A VOCOL, a SPB-20, a SPB-624, a SPB-2250, even a Equity 5 capillary are good choices.

I would choose a SPB-1701 if I had to make a single choice.

best wishes,

Rodney George
Senior Research and Development Scientist
Gas Separations Research
Supelco
595 North Harrison Road
Bellefonte, PA 16823

814-359-5737 voice
814-359-5459 fax
rodney.george@sial.com

I did find a reference to DB-1/OV-1 type phase where it elutes around C6. However, Peter is right in that it is not just a function of getting it off the column but really separting it from the other things coming off the column.

This might be tough at trace levels with FID since it has low carbon count, and an oxygen and chlorine all on one molecule. Did you want trace?

Best regards.

.

Yeah Right now I have OV101 column(packed) with me to analyse the aforesaid compound with GC/FID.

I really (This is first time to use such type of co,pound) unable to figure it out how should I get on to this aassighnment. Like more specifically I want three answers,
1. Suitable (Column--- Packed or cappilary and name of the column)
2. Limits of detection (Minimum comcentration(ppm) levels which could be detectable.
3. What are the safety measures (Type of Masks, Jackets, etc.......

I will be ever greatful to you who ever going to help me.

You should use an ECD or preferrably a HID detector to measure trace amounts of chloroethanol.

AICMM is a vendor you should check out.

www.detectorsbyaic.com
AIC Corp.
Phone: 505 890 6096
Fax: 505 890 5581

Another vendor is Valco in Houston, TX.

best wishes,

Rod

Niosh has a method for 2-chloroethanol that might act as a starting point. Search 2-chloroethanol, CDC and Niosh and you should quickly find the method in a PDF file. I would post the URL except that I cannot get my brand new Windows software to allow me to do a copy and paste. An analog man in a digital world....

Best regards.

If you need to measure chloroethanol in air that NIOSH reference is http://www.cdc.gov/niosh/nmam/pdfs/2513.pdf.

It's over 30 years old though and written in the days when the ACGIH Threshold Limit Value was 5 ppm averaged over 8hours. Since 1996 it's been 1 ppm over 15 mins.

In Europe the risk phrase is R26/27/28 (Very toxic by inhalation, in contact with skin and if swallowed). That is Hazard Band D in the system we use in the UK. We would have to think carefully before transferring a Band D liquid in the open.

For advice on control measures try the risk phrase in this system http://www.coshh-essentials.org.uk/.