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What is TAN?

http://www.chromforum.org/viewtopic.php?t=7660

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What is TAN?

Posted: Thu Jan 10, 2008 10:18 pm
by Paladin
Can anyone enlighten me as to what TAN is with regards to an HPLC Wt% assay? I'm assuming it is some kind of normalized A% for all peaks in the chromatogram?

Thanks

Posted: Thu Jan 10, 2008 10:22 pm
by Noser222
Total Area Normalization.
If you assume all the peaks have the same response factor, then if a given peak is 2% of the total area, then it is 2% (w/w) of the sample.

TAN-One more question

Posted: Mon Jan 21, 2008 3:42 pm
by Paladin
Noser222,
Thanks for your reply. That is pretty much what I thought but wanted to be sure.
Now, one more question. Does a TAN require a separate weight of the sample being run as a standard alongside the regular sample? Or does it require running the sample as a regular A% (no standard)?

Thanks
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