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How can we select the mobile phase for acidic and basic comp

Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

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How can we select the mobile phase for acidic and basic comp

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GURU
How can we select the mobile phase for acidic and basic compounds for bioanalytical methods?
guru

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tom jupille
Site Admin
Most of your questions are not amenable to short answers. All of them are covered in textbooks. I can recommend Practical HPLC Method Development by Syder, Glajch, and Kirkland.

(disclaimer: I have worked with Lloyd Snyder for the past 20 years)
-- Tom Jupille
LC Resources / Separation Science Associates
tjupille@lcresources.com
+ 1 (925) 297-5374

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AdrianF
If you want something free look at http://hplc.chem.shu.edu/HPLC/index.html

the section under pH will be useful. Also study the FAQ section on this site.
No Tswett
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