Soduim adduct ions: remedy?

[jbshan]

Dear friends,
Am using an ESI ion source for my method and I found that I have problems with Na adduct ions with my parent compound. I have dissoled the compound in 100% methanol and subsequent dilutions in 60% methanol.
How to overcome this problem so that i will get the actual response of the parent compound......URGENT

shan

[sassman]

Acid washing of your glassware and anything else that your sample comes in contact with should remove most of the Na contamination. We do this by soaking in 10% nitric acid and then thoroughly rinsing with ultra pure water. Also for your mobile phase use the highest grade water and solvents that you can obtain.