Bad %RSD

[ym3142]

I made a solution of 0.5mg/mL trimethylpropanediamine in 1 N NaOH and injected it directly to Agilent GC system. The %RSD area I got is 40%. The column is RTX 5 amine 30x0.53x1.

Any suggestions for troubleshooting. Thanks in advance

[WK]

YM3142,
Your 1N NaOH is aqueous?
WK

[ym3142]

Yes. it is Aqueous 1N NaOH

[chromatographer1]

Extract your aqueous solution into hexane or some other non-polar solvent and try it again.

Please don't shoot water and especially 1N NaOH on any GC column unless it is a Chromosorb 103 porous polymer or 10% Apiezon L with 1% KOH on Supelcoport in Glass.

best wishes,

Rod