Separating Phenylboronic acid from its trimer anhydride
Posted: Wed Oct 17, 2007 2:37 pm
I am trying to determine the purity of Phenylboronic acid, however, Phenylboronic acid can dehydrate over time to form its cyclic anhydride (AKA Triphenyl boroxin)
I have tried to separate these components by normal phase LC using Partisil 5 column, using Hexane/IPA. I get no separation and both give a v. broad peak with little retention.
Any ideas on what to try next? - i.e change mobile phase/column or try to
derivatise to form a boronate ester.
many thanks in advance
I have tried to separate these components by normal phase LC using Partisil 5 column, using Hexane/IPA. I get no separation and both give a v. broad peak with little retention.
Any ideas on what to try next? - i.e change mobile phase/column or try to
derivatise to form a boronate ester.
many thanks in advance