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electronic spikes in lc/ms

Posted: Tue Aug 28, 2007 7:53 pm
by moraespack
I noticed that electronic spikes have been appearing in LC/MS (Agilent)analysis lately. Most of the times happens when I use electrospray.
Does someone know anything about it?
thank you

Marcelo

Posted: Wed Aug 29, 2007 12:55 am
by Kostas Petritis
Electronic spikes are typical when using high electrospray voltages and/or high ionic solutions (i.e. due to arking). In negative ion mode, the problem is even worse...