suggestion for derivatising agent

[vijaykhetmalis]

Hello everyone

I want an suggestion from all of you. I have a drug containing amide group i.e. CONH2. the name of drug is levetiracetam.it is non chromophoric. i have to modify it to drug containing chromophore. so i have to attached chromophore at amide. so anyone suggest me what could be possible derivatising agent and how it is derivatised?
Plssssss reply[/b]

[Jumpshooter]

Try using Biotinylated agent. It will have a Jablonski profile that is in the range of typical flourescence excitation and emission spectra.

[Uwe Neue]

Have you tried to see it in low UV, at 210 to 215 nm with acetonitrile as your organic modifier?