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Cresol/Xylene analysis by GC/FID...need help
Posted: Wed Aug 15, 2007 3:14 pm
by Roehrs
Hi!
I have to analyse cresol and xylene by GC/FID and splitless injection mode. I use an HP-INNOWax (PEG) column.
Can you send me a good method for the analysis?
What is the best temperature programmation for? And which solvents and internal standard can I use?
Thank you!
Posted: Wed Aug 15, 2007 4:03 pm
by chromatographer1
Generally beginning at 60°C and programming the oven at 4°C until your peaks elute will work.
Almost any solvent is recommended except water or methanol.
I would not use an injector, column oven, or detector temperature far above 200°C to avoid damaging the column.
good luck and best wishes,
Rod
Posted: Thu Aug 16, 2007 1:20 am
by Consumer Products Guy
Use a carrier gas oxygen trap with PEG columns.
Posted: Thu Aug 16, 2007 6:29 am
by Roehrs
And which internal standard is good for the method?
Posted: Thu Aug 16, 2007 12:12 pm
by chromatographer1
The internal standard should chemically be similar to the analytes you are measuring.
In your case diethylbenzene? Cumene? Even Toluene?
You could also use a simple alkane if that is all you have available.
best wishes,
Rod
Posted: Wed Aug 22, 2007 1:44 pm
by Roehrs
The producer of the column wrote me that I can use any solvent I want. Also water and methanol! So, the best choise would be water as solvent.
What do you think about it?
Posted: Wed Aug 22, 2007 2:13 pm
by chromatographer1
I would NOT use water or methanol if possible. Ether would be a possibility if you need to make sure any trace water is dissolved.
I would also avoid acetone but might consider 2-butanone.
I WOULD USE
any hydrocarbon, aromatic, or chlorinated hydrocarbon solvent.
For example: pentane, hexane, heptane, tetraethylbenzene, methylene chloride, chloroform, etc
Be certain that cresol and xylene do not coelute with the solvent you pick.
best wishes,
Rod