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IC: CarboPac PA1 - Mobile Phase Compatibility

Posted: Mon Jul 30, 2007 3:24 pm
by Rob Burgess
Is this column compatible with a 2.0 M NaCl as a mobile phase? A colleague of mine has inherited a transfer of a method that uses this and is experiencing reproducibility problems. Is it possible that this buffer salt can damage the stationary phase?

Posted: Tue Jul 31, 2007 4:02 pm
by Mark Tracy
I asked a couple people here, and they can think of no a priori reason for 2M NaCl to damage the column. What is the nature of the reproducibility problem? Drifting retention time? Can't reproduce someone else's results?