IC: CarboPac PA1 - Mobile Phase Compatibility

[Rob Burgess]

Is this column compatible with a 2.0 M NaCl as a mobile phase? A colleague of mine has inherited a transfer of a method that uses this and is experiencing reproducibility problems. Is it possible that this buffer salt can damage the stationary phase?

[Mark Tracy]

I asked a couple people here, and they can think of no a priori reason for 2M NaCl to damage the column. What is the nature of the reproducibility problem? Drifting retention time? Can't reproduce someone else's results?