Volatile chelating agent for LCMS?

[Pegry]

Dear everybody,

I would like to know if there are some kind of volatile chelating agents that could be used in LCMS (ESI). Do you know of some compounds that could substitute EDTA for LCMS analysis?

Thanks in advance for any comments,

Have a good day,

Davide

[HW Mueller]

Some crown ethers?

[AICMM]

Not an LC bob here, so forgive me if I sound ignorant. I thought acetate, citrate, ascorbate, were all weak chelating agents. If so, they should be volatile enough, shouldn't they?

Best regards.

[Bryan Evans]

We have nice peak shape for chelating compounds on our phases
using LC-MS conditions (i.e. without EDTA). If you email
me, i'll forward the data on to you.

[HW Mueller]

Bryan, it would be nice if you could disclose some examples here.

[Bryan Evans]

Hi Hans -

I'll email you the link. I'm afraid it could be considered marketing material - not really appropriate for this forum, thank you.

[HW Mueller]

If it contributes to knowledge, I think most of us would forgive the marketing?

[tom jupille]

Bryan, I think you'd be "in the clear".

From the "Policies" statement:

Participants are welcome to discuss specific products or services by name. If you have a product which solves a posted problem, go ahead and talk about it, but material that actively promotes the sale of a product or solicits participants will be deleted from the message board. Unsubstantiated opinions or "trashing" of commercial products also will be removed.

Translated: providing details of a separation on your column or instrument as part of a discussion of a user question is OK (actually, encouraged). Posting a price list or starting a new thread with one of your applications is not.

"Spam" is a lot like pornography: it may be hard to define, but most people recognize it when they see it.

[Bryan Evans]

Hi Tom -

Thank you very much. I'm sure I speak for everyone here when I say we are all very grateful for your work here both as a moderator and for your expert advise.

Below is a link for an antibiotic compound injected into our Cadenza CD-C18 column using only formic acid:

http://www.imtakt.com/TecInfo/TI059E.pdf

[promochrom]

Hi Pegry,

There are some mixed mode columns that bond chealating or ion pair agent to the column packing. With one column you can even handle hydrophobic organic compunds and inorganic ions in one run. You can find many intersting application examples from website www.sielc.com or ww.gc-lc.com.

Regards.