separating impurities in phenol

[phenol guy]

I'm having trouble finding the best column to separate cyclohexanol (b.p. 161C), cyclohexanone(b.p. 156C), benzaldehyde (b.p. 178) and anisole (b.p. 154C) from each other in Phenol. The concentrations are very low <10ppm each in molten phenol. The best I can do so far is a supelco wax 10 60 m with a low initial temp then a big push and bakeoff. What do you guys suggest? New customers are great until you get there specifications.

[chromatographer1]

I can tell you what won't work well. Anything non-polar.

My quess from the structures is that an intermediate polarity would be the best quess, a 1701 phase or a Vocol, for example.

The main issue with that column is "where would phenol elute?"

Sorry I don't have the data at hand to share with you.

best wishes,

Rod

[gcguy]

Try a CPsil 13 25mx0.32mmx.2um. We use this column for phenol as an impurity, as as a few other compounds similar to the ones you are interested in.

GCguy

[yaoguocan]

have you try HP-5 or some similar colum if not i strongly recomment you to have a try

[chromatographer1]

I do not believe a 5% Phenyl column will work.

It requires a more polar column that a 5% phenyl.

Ov-1701 or a OV-225, or a Vocol type column may work.

best wishes,

Rod