Chromatography Forum

What is cold syringe?


regards,

Cold is low temperature. Syringe is a device for injection. If there is anything else you want to know you should probably ask a more detailed question.

Peter

Peter,

Thanks for your reply.
This is related to a low valatile sample preparation: whre one has to transfer the refrigerated sample using a cold syringe.
I checked with some of the local syringe distributors, but they are unable to procure anything named "cold syringe".
I checked it on net, the name is used for some clinical sample preparation article, but with no deatils.
Can someone help?
regards,

I assume that you mean the transfer of low levels of volatile components from a cold container. The syringe would need to be cold also so as not to heat up the sample during transfer so you should just use a regular syringe but keep it in the refrigerator or freezer before the transfer. You may want to wear some king of gloves to prevent heat transfer from your hands. Good luck!

Chromatocrat,
if you are ever able to procure a cold syringe commercially, I would certainly appreciate being informed as to the source.

Chromatocrat, I would go with skunked once's advice, you are not going to be able to buy a cold syringe. Beware that when syringes are chilled the plungers are a looser fit in the barrel

Hans, if you really want a cold syringe I could probably supply one, but it would have to ship on dry ice, and unless you keep it in the deep freeze it would have a very short shelf life

Peter

Just a note, based on my experiences using cold syringes for volatile hydrocarbons. I prefer to cool syringes to fridge temperatures ( 3C ), which prevents issues of blocked needles from wet samples that arise with sub-zero temps.

Many syringes have a bonded metal needle, luer fitting, or screw thread for replaceable needles at the front of the barrel. If you put them in freezer ( -17C ) temperatures, you can crack the glass or adhesive and get a variable leak.

You can also crack the glass if you leave the metal plunger in a plunger-in-barrel syringe, presumably because the glass cools faster than the metal. Having destroyed a couple of syringes, I'm not sure of the theory, but the reality was annoying.

I usually prefer to use guided plunger-in-barrel syringes and withdrawn the plunger from the barrel when either cooling or warming.

Please keep having fun,

Bruce Hamilton

Peter,
that´s very disillusionary. You only have a syringe which is cooled, but not a "cold syringe"? I was going to carefully examine this cold syringe to be able to invent a hot syringe. Actually, thought this to be chicken feed as I was thinking that a "cold column" would be The commercial hit.

Actually I have cracked syringes when heating them, so I suspect using teflon plungers is the better way to avoid purchasing new syringes.

Chromatocrat,

try not to ask questions at the end of the month. The mental condition of chromatographers seems to degrade around this point. But fresh next month we will all be ready to answer new challenges with vigor and candor.

Have a good weekend,

Rod

Some chromatographers have had to run so many samples near month end to please number crunchers that their brains are wasted.
I find that copious quantities of lager improves this feeling by Monday morning at the expense of a dip early Saturday morning!

Dear All,

Thanks a lot with lots of suggession.


I got my answer as,
-there's no device as cold syringe but it's syringe kept at low temperature, but not refridgerated.

regards,

I think you got the idea.

It depends upon the analytes you are transferring and how much temperature affects their stability and volatility in the syringe.

There is cold and then there is COLD. It might be 4°C is cold enough.

Skunked_once's comments about heat transfer from warm hands is quite valid and really essential.

Analytes like butane or 1,1-dichloroethene are difficult to work with and the list is almost endless.

Good luck with your analysis.

Rod