Mobile phase expiration

[rwk27834]

Is there a standard in the industry regarding expiration dating of HPLC mobile phases? Are there FDA guidelines on this? Or is it different company by company?

[Mark Tracy]

This topic has been discussed here. You might try to search the archives. If you are in a regulated environment, you need to establish some kind of policy, and provide evidence to justify it. You might determine that buffer A keeps for 2 weeks and make that your default policy, only later to discover that buffer B grows bugs within that period. How you document and deal with the issue is more important than anything else.