I understand that most method validations are written from the point of view of pharmaceutical research, e.g. quantitation of drug from plasma. However, my application of LC/MS is simply for purity and identity of a given synthesized piece of DNA (from 8 to 40-mers). We have a good LC/MS method, but it needs to be validated. Does anyone have any experience with validating this type of method, or do you know of any resources that might help?

Thanks