do you have peak shouldering/splitting cases
Posted: Sat Mar 03, 2007 1:07 pm
in last topic"buffer pH vs analyte pka about peak splitting"
we concluded that buffer pH value being equal to analyte pka value is not the root cause for peak shouldering/splitting, and the true reason is the formation of mutilple phases of mobile phase.
please present us your buffer-related shouldering/splitting cases which are for/against this conclusion so you can help everyone to fully understand this physical chemistry issue.
we concluded that buffer pH value being equal to analyte pka value is not the root cause for peak shouldering/splitting, and the true reason is the formation of mutilple phases of mobile phase.
please present us your buffer-related shouldering/splitting cases which are for/against this conclusion so you can help everyone to fully understand this physical chemistry issue.