choice of QC's concentrations
Posted: Thu Nov 30, 2006 1:32 pm
How should the concentrations for QC samples be chosen? Is it ok if they are identical with calibrator concentrations? All I could find on this topic from FDA was that low QC must be within 3x from LLOQ.
I see that in literature typically QC's concentrations are different from calibrators. What's the rationale behind that?
I see that in literature typically QC's concentrations are different from calibrators. What's the rationale behind that?
