Chemometrics
Posted: Sun Oct 22, 2006 4:52 pm
by dilli
I would like to know information , firstly on, how we perform experimental design for a hplc method , its robustness and also on optimization of a HPLC method using chemometric tools like neural network.
Posted: Mon Oct 23, 2006 8:25 am
by PJ8
For robustness we use design experiment6 (actaully I think it's now DX7)
This gives factorial experiemental design and good data processing of multiple components.
For method design see Tom's list in another post:
http://www.sepsci.com/chromforum/viewtopic.php?t=4808
Posted: Mon Oct 23, 2006 8:35 am
by bartjoosen
An alternative to Design Experiment is R (
www.r-project.org) in combination with the AlgDesign package.
Although it's a bit difficult to start, you can do everything you want with the design of experiments. But it's not so graphical and intuitive as desigh experiment.
Bart