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Hb A2 seperation

Posted: Thu Sep 21, 2006 9:28 am
by hadye
Hello everybody,
I am new member of this forum and still novice in HPLC, I am trying to seperate different Hb types on HPLC 1100 series. The problem that I have is that I cannot seperate HB A from A2.

I am using a cation exchange column 2.5ux100mm. I tried using phoshate buffer and tris for pH but still I cannot seperate A2. All the peaks whether A S F C can be seperated but always A2 is hidden in the A tail in chromatogram

Can anyone help me in this issue