How to calculate mass % from the GC-MS peak area %?

[GC-td123]

Hi

The last row in the below table represents the GC-MS peak area % of different compounds. Is it possible to calculate mass % of the compounds from the GC-MS peak area %?.

How do we calculate mass %, if the sample contains several compounds?


peak R.T. first max last PK peak corr. corr. % of
# min scan scan scan TY height area % max. total
--- ----- ----- ---- ---- --- ------- ------- ------ -------
1 1.266 27 30 42 PV 814190 7953291 2.59% 0.576%
2 1.361 42 45 57 PV 2668510 26734157 8.70% 1.936%
3 1.469 57 63 70 PV 2 1389933 37432591 12.19% 2.710%
4 1.525 70 73 79 VV 1618073 18999414 6.19% 1.376%
5 1.954 79 144 155 VV 3380277 307129642 100.00% 22.236%

6 2.059 155 161 173 PV 5631411 81559860 26.56% 5.905%
7 2.203 173 185 192 VV 113488 2966303 0.97% 0.215%
8 2.331 192 206 212 PV 281227 4253436 1.38% 0.308%
9 2.434 212 223 243 VB 2 280856 7871431 2.56% 0.570%
10 2.706 253 268 274 PV 1347139 18481713 6.02% 1.338%


Thanks for your time.

[HPLC chemist]

No. For each peak you need a 'response factor' (mass or concentration versus detector response) since each molecule will have a different detector response. %Peak Area is a 'meaningless' number especially since it even includes the solvent peak.