SIM METHOD
Posted: Sun Mar 26, 2017 6:02 pm
by envirogeechem
Pls. any one can help me in developing SVOC analysis by SIM method
Re: SIM METHOD
Posted: Sun Mar 26, 2017 7:27 pm
by HPLC chemist
You can adapt this. I don't see any atoms in common (except Carbon) so I doubt you can remake the wheel and develop a SIM method.
https://www.thermofisher.com/ca/en/home ... lysis.html
Re: SIM METHOD
Posted: Tue Mar 28, 2017 6:06 pm
by Bigbear
Look at EPA 525.3.
Re: SIM METHOD
Posted: Tue Mar 28, 2017 10:20 pm
by James_Ball
I made a SIM method for the full Appendix 9 VOC list, just used the normal quant ions and qualifier ions from a full scan method, then divided them up into time segments to try and keep it to about 15-17 ions per segment with 10ms dwell times. Use a full scan run to find retention times, then adjust the starting points for each segment from that using the same temperature program. It takes time but it isn't too difficult.