Chromatography Forum

Chromatography Forum is a public discussion group where you can post questions, news, or messages of interest to chromatographers everywhere, but you must be registered to participate (registration is FREE). If you are a registered user, please log in.
http://www.chromforum.org/

Nitrogen purity in LC-MS/MS

http://www.chromforum.org/viewtopic.php?t=41131

Page 1 of 1

Nitrogen purity in LC-MS/MS

Posted: Mon Mar 06, 2017 7:30 am
by alcorn
Hi everybody,

Do anyone know what is the effect of N2 purity (for collision cell) in LC-MS/MS?

I used to N2 99.5% (instead of 99.999% as recommended by the vendor) without any problem. Is it mandatory to switch to higher purity or it may damage my instrument؟

Thanks

Re: Nitrogen purity in LC-MS/MS

Posted: Mon Mar 06, 2017 7:41 am
by tkubowicz
Hello

Collision cell gas requires higher purity than the gas used as drying gas.

Please see p.11 in document below:

http://www.ingenieria-analitica.com/dow ... rev_03.pdf

It won't damaged instrument but if you'll have problems with your methods one of the questions could be: what is N2 purity?

Regards

Tomasz Kubowicz
All times are UTC
Page 1 of 1
Powered by phpBB® Forum Software © phpBB Limited
https://www.phpbb.com/