Chromatography Forum

Hi, could someone please explain what is meant by 'column bleed' in GC.

Is it the wearing off of stationary phase in the column as the column ages?

Also would it be correct to say that there are normal (normal background signal by the stationary phase) and abnormal (a rise in baseline)?

thank you.

Hi

Basically, you are correct

Try looking at these articles

http://www.sge.com/support/training/col ... lumn-bleed

http://www.sigmaaldrich.com/technical-d ... s-low.html

Regards

Ralph

GOM: Thank you for the links..

Would it also be correct to say that minors peaks (besides peaks of analytes of interest) on the baseline of the chromatogram represent noise?

Thank you.

Hi chemgc779

Would it also be correct to say that minors peaks (besides peaks of analytes of interest) on the baseline of the chromatogram represent noise?

No, noise on the baseline signal is a bit like the background hiss on an audio signal.

Does that help?

I wonder if you would be better posting your queries on the Student section for better help from the forum

Kind regards

Ralph