Theoretical plate? [July 27, 2004]
Posted: Sun Aug 29, 2004 5:49 pm
By syx_gf on Tuesday, July 27, 2004 - 06:14 pm:
What is the simple definition of column plate? Why is it called "plate", though in consist of round particles not pieces of plates?
Please do not give me the formula.
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By Bob on Wednesday, July 28, 2004 - 06:01 am:
How far an analyte travels relative to how wide it gets.
high plate count then means your analyte can travel a long distance with very little broadening.
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By tom jupille on Wednesday, July 28, 2004 - 09:15 am:
The original model of chromatography dynamics used the same mathematical formalism that applies to distillation (a series of discrete equilibrations between two phases). In a process-scale distillation column, this can occur on actual plates. Most chromatography is a continous process, so the "plates" are only theoretical.
The "plate model" is no longer used much, but the term persists (as Bob pointed out) as a measure of the ratio of peak broadening to migration.
What is the simple definition of column plate? Why is it called "plate", though in consist of round particles not pieces of plates?
Please do not give me the formula.
-------------------------------------------------------------------------------------------------------
By Bob on Wednesday, July 28, 2004 - 06:01 am:
How far an analyte travels relative to how wide it gets.
high plate count then means your analyte can travel a long distance with very little broadening.
-------------------------------------------------------------------------------------------------------
By tom jupille on Wednesday, July 28, 2004 - 09:15 am:
The original model of chromatography dynamics used the same mathematical formalism that applies to distillation (a series of discrete equilibrations between two phases). In a process-scale distillation column, this can occur on actual plates. Most chromatography is a continous process, so the "plates" are only theoretical.
The "plate model" is no longer used much, but the term persists (as Bob pointed out) as a measure of the ratio of peak broadening to migration.