Chromatography Forum

Chromatography Forum is a public discussion group where you can post questions, news, or messages of interest to chromatographers everywhere, but you must be registered to participate (registration is FREE). If you are a registered user, please log in.
http://www.chromforum.org/

ELSD

http://www.chromforum.org/viewtopic.php?t=3476

Page 1 of 1

ELSD

Posted: Wed Feb 22, 2006 5:53 pm
by Sarahr
Hi
Just started using an ELSD microbore system, having problems with obtaining a baseline with flow rates of a 150 microlitres/min. I am using milli-q, methanol and formic acid for the solvent system.
I am new to this equipment so any suggestions will be more than greatful
Cheers
Sarah

Posted: Wed Feb 22, 2006 11:29 pm
by Mark Tracy
A new ELSD takes time to blow the cobwebs out. The gas supply lines need to be very clean; if you don't have a sub-micron filter, get one. Also, the ELSD can tell you things about your water system that the conductivity meter won't tell you; if you have an alternative water source, see if that makes a difference. Finally, double-check all the advice in the manufacturer's instruction manual; there are some non-obvious things about the installation and setup of some models.
All times are UTC
Page 1 of 1
Powered by phpBB® Forum Software © phpBB Limited
https://www.phpbb.com/