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quadratic regression

http://www.chromforum.org/viewtopic.php?t=32191

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quadratic regression

Posted: Wed Jun 15, 2016 6:18 pm
by jiangds06
waters micromass triple quad is used for the quantification, why i always get quadratic regression from lcmsms analysis.

Re: quadratic regression

Posted: Wed Jun 15, 2016 6:46 pm
by Steve Reimer
Is this unexpected in the analysis you are doing? Are you operating near the lower sensitivity limit? How far off linear are your calibration curves?

Re: quadratic regression

Posted: Fri Jun 24, 2016 3:12 pm
by jiangds06
our lowest peak at LLOQ. linear regression give me r2 at 0.9.

Re: quadratic regression

Posted: Fri Jun 24, 2016 5:51 pm
by James_Ball
Ionization efficiency is often related to concentration if using Electrospray source. I often see quadratic responses on our LCMSMS.
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