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TFA and APCI
Discussions about GC-MS, LC-MS, LC-FTIR, and other "coupled" analytical techniques.
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Why does TFA has less effects on APCI than ESI in term of ion supression?
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This efect depend of the kind of ESi probe, because in ESI probe with thermal option, you can used the hot to eliminated the ion suppression efect. The same hot in APCI "desolvated" the matrix (in general) to eliminated the excess of ion suppression efect.
Alejandro
Alejandro
Applications Chemist in Mass Spectrometric
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