Chromatography Forum

Posted: **Wed Oct 19, 2005 2:12 pm**

hello,
can someone suggest an internal standard for tamoxifen which is seen after the tamoxifen peak.

thank you,
rima

Posted: **Thu Oct 20, 2005 11:08 pm**

4-methoxytamoxifen has been used:
http://www.clinchem.org/cgi/content/abstract/33/9/1608

I suspect a google search would turn up other candidates.

Posted: **Thu Oct 20, 2005 11:48 pm**

i have a method for tamoxifen and its metabolites..

see

http://littledomain.com/james/files/matrix_effects.htm