Hello all,

what is your preferred wash solvent for needles and buffer loops (PEEK and stainless) for a lipidomics LC method?

We are analyzing lipid extracts containing polar lipids, fatty acids, and triglycerides (TAG). In the past there have been issues with TAG carry-over. We are using a Dionex 3000 system.

I am trying to get some ideas. I am currently using 5/4/1 IPA/MeOH/H2O, but I am considering using 75/25 IPA/MtBE.

Thanks!