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chiral column

Posted: Fri Oct 07, 2005 3:32 am
by A.L.N. MURTHY
Dear friends,
Can you recommend the chiral column for isomers seperation of SERTRALINE Hcl.

HPLC determination of sertraline

Posted: Fri Oct 07, 2005 7:02 am
by michael.k raj
Dear Murthy,
Hope this will be useful to you.This method doesn't use chiral column even to separate the four isomeric peaks
-Karunai Raj
Journal of Pharmaceutical and Biomedical Analysis
34 (2004) 239–245
Short communication
HPLC determination of sertraline in bulk drug, tablets and capsules
using hydroxypropyl--cyclodextrin as mobile phase additive
Deying Chen, Shumin Jiang, Yuying Chen, Yuzhu Hu∗
China Pharmaceutical University, 24 Tongjia Lane, Nanjing 210009, China
Received 6 May 2003; received in revised form 19 August 2003; accepted 19 August 2003