Advertisement
Chromatography Forum

Analysis of Bisoprolol hemifumarate

Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

2 posts Page 1 of 1
Topic locked

Analysis of Bisoprolol hemifumarate

avatar
Provetech
Hi, we're trying to replace Perchloric acid buffer by an volatile one for the LC/MS analysis of Bisoprolol hemifumarate. Could anyone tell me what buffer i should try (TFA buffer dont give good peak shape)
PS: Concentration is 2mL/L of perchloric acid.

Thanks

avatar
Mark Tracy
Have you considered longer-chain perfluoro acids? pentafluoropropionic or heptafluorobutyric?
Mark Tracy
Senior Chemist
Dionex Corp.
Topic locked
2 posts Page 1 of 1
Return to “Liquid Chromatography”

Who is online

In total there are 36 users online :: 1 registered, 0 hidden and 35 guests (based on users active over the past 5 minutes)
Most users ever online was 11462 on Mon Dec 08, 2025 9:32 pm
Users browsing this forum: Google [Bot] and 35 guests

Latest Blog Posts from Separation Science

Separation Science offers free learning from the experts covering methods, applications, webinars, eSeminars, videos, tutorials for users of liquid chromatography, gas chromatography, mass spectrometry, sample preparation and related analytical techniques.

Subscribe to our eNewsletter with daily, weekly or monthly updates: Food & Beverage, Environmental, (Bio)Pharmaceutical, Bioclinical, Liquid Chromatography, Gas Chromatography and Mass Spectrometry.

Liquid Chromatography

    Gas Chromatography

      Mass Spectrometry