Chromatography Forum

Hello,
I have hplc which uses W2690/5, 996 PDA, TCM. Yesterday night while running samples it stopped in middle of run and said instrument failure. I restarted the system, did monitor if the instrument is working.. it run last night after restarting. But, today morning its not running. It says, system idle: instrument failure
Can somebody help me telling what to check?

I think there is must be error code on 2690 screen or in Millennium program.
If it works with samples and stopped middle make sure your vials are all same and correct type.
This information are on table B-4 in 2690 manual.

... or in your Message Center if you're running Empower or one of its ancestors.

Most often it’s pressure limit exceeds that cause such a behaviour.
Could be upon sample injection, could be during a gradient that pressure increases over limits due to viscous mobile phase composition or precipitations.
Check the limits in the instrument method and correct if they are unreasonably narrow or trouble-shoot the chemical part of the matter.

Best Regards