COLUMN FOR SEPARATION OF ALCOHOLS

[jmsalcines@gmail.com]

Hi everybody,
Wich type of capilary column could I use to separate small amounts of alcohols (0,1% v/v) aprox. (methanol, ethanol and isopropyl) into another solvent as methylene clorhyde or isopropyl alcohol.
We used a packed column DC550 type but we want now switch to capilary.
Any help would be very appreciate.

[lynoguchi]

Hello jmsalcines,

As reference, you can use the columns indicated in ASTM D5501 or EN 15721.
The ASTM D5501 uses a non-polar methyl-silicone column with dimensions of 100 m x 0.25 mm x 0.5 um or 150 x 0.25 x 1.0 m.
The EN 15721 uses a CPWax 57 CB (25 m x 0.25 mm x 0.2 um) or a DB 1701 (60 m x 0.25 mm x 1.0 um).

All columns can make the separation of methanol, ethanol and iso-propanol, the only difference is the analysis time and method configuration.

Regards.

[jmsalcines@gmail.com]

thank you so much, lynoguchi

[MSCHemist]

Residual solvents everyone has a column optimized for it Restek, Agilent, Zebron, Macherey Nagel, Supelco etc. It is a very popular GC method.

[MSCHemist]

btw when looking at small very volatiles you are better off picking a high boiling solvent that will elute after the analytes like dimethyl acetamide DMSO DMF or limonene. Otherwise most columns seem to be cyanopropyl based like 624. I use a wax anf ethanol and isopropanol can be tough to separate.