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Help me please in finding a procedure or methods

Posted: Sat Jan 10, 2015 1:18 am
by namer2014
Hi guys, please help me

We have in our city some kind of vegetable that is usually spiked with pesticides ( mainly one compound). This food is consumed quite heavily.

My intended aim is to see how long this compound will stay, I mean i want to study its degradation and its main metabolite ,, every thinks really

I search the literature but i feel i couldn't find my aim

My question is

Do you know some good procedure to follow experimentally. I mean do i just choose 10 times same food and spike with the pesticide and measure recovery. I had bad experience before of refusing my work so i really need some excellent paper or regulatory procedure to follow

I have access to all papers if you could put the link here

Thanks in advance

Re: Help me please in finding a procedure or methods

Posted: Mon Jan 12, 2015 2:58 pm
by KM-USA
Spike at target level and lower, check precision, accuracy, linearity, etc., as for cGMP method validation.

Identify the pesticide of interest if you want more help from people here.