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How to calculate LOD and LOQ from calibration curve

Posted: Tue Dec 23, 2014 4:30 pm
by SamNas
Dear All,

I am new at method validation. I have followed ICH guidelines and have got the data for six days. I have made the 6 point calibration graphs. can anyone guide me how to calculate LOD and LOQ from this graph. I ll appreciate if anyone can share a worked excel sheet with me.

Re: How to calculate LOD and LOQ from calibration curve

Posted: Wed Dec 24, 2014 6:38 pm
by tom jupille
A screen capture video runs through it:
http://www.lcresources.com/sandbox/LOD-LOQ.html