Chromatography Forum

Is anyone familiar with the VETRANAL analytical standards by FLUKA?
Are these standards useable as a quantitative standard for HPLC? Are they retraceable to USP/EP?

Or are these standards only suitable for FTIR, TLC, peak identification etc?

I'm not familiar with these VETRANAL standards, but Fluka (or Sigma-Aldrich - no wait, it's Merck, now, right?) actually has pharmaceutical secondary standards which can be used for quantitative analysis:

http://www.sigmaaldrich.com/analytical- ... ndary.html

They are traceable to USP/EP/BP. You'll get a comprehensive certificate for each batch of standard including all test results according to the pharmacopoeias.

Thanks for the link! Those secondary standards might be quite useful at our laboratory.

The certificates that come with the VETRANAL standards specify an assay given in area%. So I guess they're not traceable to an other standard.
But area% has not really anything to do with the activity or purity of that standard. That's why I'm doubtful about the quantitative use of these standards.

Hi everyone.

Does anyone knows the meaning of Vetranal grade for analytical standards?... can I used it for analytical quantitation.. do I have to certify it according to USP?...

I´m new in the bussiness so I would be very grateful for any help.

They cannot be used as primary standards (USP, EDQM, JP...), but they can be used as secondary standards if you have a suitable SOP. Typically, a standard is identified and characterized by MS, UV, NMR, FTIR... Thus, they should have an appropriate 'Certificate of Analysis (COA)'.

But there is no relevant guidance that I know of.