Chromatography Forum

Hellow experts ,

I want to perform the derivatization of water soluble sodium salt and the sulfate salt. Which type of derivatization reagent is suitable for the derivatization. Both of the salts are aliphatic in nature and does not have any chromophoric group, how can I derivatized and analyze such type of salts on HPLC

Praveen

The compound contains amino group with alkyl chain

I'm not sure, look up Waters AccQTag? Works rather well with amino acids.

a "sodium salt with amino group" is a bit vague description... If you want help to renovate a house, you don't post a request like "need help to renovate an house with doors and windows". Can you give use more details on your compound and your attempts at analyzing it so far?

For me that sound more like an Ion Chromatography task without derivatization as the components are water soluble.