Chromatography Forum

Dear Specialists, please I need a piece of your advice regarding the good equipment for dioxin lab.
Unfortunately, I'm not the chromatographist so I know quite a little.
I work for a reselling company and we have the enquiry to set up the lab for dioxin analysis of the foodstaff such as sunflower and rape oils, oil meals, etc.
I need to find the appropriate equipment\manufacturer for sample purification\extraction and identification\quantitation of dioxines.
I need to find the equipment other than Thermo.
Thank you all very much!

The best extraction kit is FMS http://www.fms-inc.com/
Then the cost really sky rockets. You should buy an Autospec from Waters which is the tradional way to go as you need High resolution GC/MS and a sector is the only way to go. There are people looking at changing the legislation to allow triple quads to be used which would greatly reduce the cost. The new accurate Mass GC/TOFs might also be an alternative.

The cost of extraction and buying the kit is usually a barier to setting up a lab. Here in the UK I think there are only two acreditted labs

I need to find the equipment other than Thermo.

what's wrong with thermo ??

Dear Specialists, please I need a piece of your advice regarding the good equipment for dioxin lab.
Unfortunately, I'm not the chromatographist so I know quite a little.
I work for a reselling company and we have the enquiry to set up the lab for dioxin analysis of the foodstaff such as sunflower and rape oils, oil meals, etc.
I need to find the appropriate equipment\manufacturer for sample purification\extraction and identification\quantitation of dioxines.
I need to find the equipment other than Thermo.
Thank you all very much!

Might I be so bold as to suggest that trawling the internet for advice is not adding much value to the service that you are charging your client for, and that asking for free advice that you are then going to sell on is rather sharp practice ?

Peter

The best extraction kit is FMS http://www.fms-inc.com/
Then the cost really sky rockets. You should buy an Autospec from Waters which is the tradional way to go as you need High resolution GC/MS and a sector is the only way to go. There are people looking at changing the legislation to allow triple quads to be used which would greatly reduce the cost. The new accurate Mass GC/TOFs might also be an alternative.

The cost of extraction and buying the kit is usually a barier to setting up a lab. Here in the UK I think there are only two acreditted labs

Thanks a lot!!!
Yes, Autospec from Waters is my working option. What I would love to know is there any other manufacturers except of Thermo and Waters, because I didn't find any. And you are right, we cannot buy any quads as they are not listed in EU Directives as methods suitable for dioxin analysis, so we have to choose only GC/HRMS or GC/MSMS. Unfortunately this limits us greatly.
Again, thank you very much!

I need to find the equipment other than Thermo.

what's wrong with thermo ??

Thermo is OK
I need to find an alternative.

Might I be so bold as to suggest that trawling the internet for advice is not adding much value to the service that you are charging your client for, and that asking for free advice that you are then going to sell on is rather sharp practice ?

Peter

Peter, thank you very much for your informative feedback!
FYI, I don't have client yet as I have little to propose - there are not many instruments. That's why I ask the professional community for help as no one in the world knows everything.
If you really know the good instrument you are free to share the model.

FYI, I don't have client yet

"I work for a reselling company and we have the enquiry to set up the lab for dioxin analysis"

???

Peter

"I work for a reselling company and we have the enquiry to set up the lab for dioxin analysis"

???

Peter

Peter, we have enquiry to propose the equipment. Nobody pays for the proposition.

Talk to Geoff at GB Scientific for info on both Thermo and Autospec Dioxin systems. There are no real alternatives to either of the above systems for 1613 or 8290 analysis

Talk to Geoff at GB Scientific for info on both Thermo and Autospec Dioxin systems. There are no real alternatives to either of the above systems for 1613 or 8290 analysis

I was afraid of that.
But thanks a lot!!!

Hello,
are those instruments suitable for dioxin analyses: PerkinElmer Clarus 560 S GC/Mass Spectrometer 120/230 V or Clarus SQ 8 GC Mass Spectrometers?
http://www.perkinelmer.com/Catalog/Product/ID/N6658627
http://www.perkinelmer.com/Catalog/Fami ... ectrometer

Both are quads-unit resolution by definition. HRMS for Dioxins requires 10,000 at 10% baseline resolution, according to EPA specifications. Most of the labs running today are usually at 12,000-13,000 at 5% baseline resolution which means neither quads nor TOFS although recent EU notifications are suggesting screening using triples (I assume M-HCL) which I'm not sure how useful in the presence of high PPE contamination will work out. Be aware that Lab prep is fairly intensive for Dioxin analysis depending on matrix involved and qualified instrument operators don't come cheap.

Both are quads-unit resolution by definition. HRMS for Dioxins requires 10,000 at 10% baseline resolution, according to EPA specifications. Most of the labs running today are usually at 12,000-13,000 at 5% baseline resolution which means neither quads nor TOFS although recent EU notifications are suggesting screening using triples (I assume M-HCL) which I'm not sure how useful in the presence of high PPE contamination will work out. Be aware that Lab prep is fairly intensive for Dioxin analysis depending on matrix involved and qualified instrument operators don't come cheap.

Thanks a lot!!!!