HPLC determination of trace acrylamide in food
Posted: Tue Jul 08, 2014 10:10 pm
Our lab is interested in getting a HPLC for trace acrylamide detection in starchy food (bread, potato chips, etc). But we have very tight budget to get a HPLC-MS or HPLC-MS/MS. So we are wondering if there is any other lower-cost detector equivalent to MS in terms of sensitivity or other methods (type of columns, sample clean-up, derivatization, etc) exist. The dynamic linear range of acrylamide we are looking for is 10-1000 ppb.
So far Waters contact me about their latest QDa Mass Detector with a affordable price. But I have no idea how this new instrument will work. Anyone recommend it? What is the disadvantage or any improvement required? What is the LOD, LOQ and linear range of QDa? Is QDa easier to operate and maintain compared to conventional MS? I used to work with Agilent 1200, never work with Waters before, so I am kind of worried about different operation system.
So far Waters contact me about their latest QDa Mass Detector with a affordable price. But I have no idea how this new instrument will work. Anyone recommend it? What is the disadvantage or any improvement required? What is the LOD, LOQ and linear range of QDa? Is QDa easier to operate and maintain compared to conventional MS? I used to work with Agilent 1200, never work with Waters before, so I am kind of worried about different operation system.