Chromatography Forum

Chromatography Forum is a public discussion group where you can post questions, news, or messages of interest to chromatographers everywhere, but you must be registered to participate (registration is FREE). If you are a registered user, please log in.
http://www.chromforum.org/

Noise measurement for s/n to meet GMP

http://www.chromforum.org/viewtopic.php?t=24953

Page 1 of 1

Noise measurement for s/n to meet GMP

Posted: Fri Jun 13, 2014 11:03 am
by Rob Burgess
Hi there,

Our CDS system can calculate baseline noise in a variety of way incluidng 1) peak to peak and 2) average peak to peak noise.

The EP and USP are a bit vague in describing what is the "official way" to measure noise. Is it acceptable to use No. 2) - average peak to peak noise for GMP system suitability determinations?

Re: Noise measurement for s/n to meet GMP

Posted: Fri Jun 13, 2014 11:30 pm
by mattmullaney
Hi Rob,

Try this link:

http://www.waters.com/webassets/cms/sup ... ower_2.pdf

Perhaps this will help...Waters recommends Peak-to-Peak as opposed to the Average Peak-to-Peak Noise.

Best Wishes!
All times are UTC
Page 1 of 1
Powered by phpBB® Forum Software © phpBB Limited
https://www.phpbb.com/