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- Posts: 14
- Joined: Fri Oct 18, 2013 1:54 am
Dear all,
I am trying to run loop injections using TSQ Qantum max ESI for a mass range >1000da and I find poor sensitivity.
I am using 0.1% formic acid+ MeCN (50:50) 0.1ml/min as the mobile phase in the positive ion mode, the samples are about 2mg/ml and I still find it hard to detect mol wt >1000.
Is there anything I can do to improve sensitivity? The manual says, the TSQ is set up for mol wt up to 3000.
Any suggestions which could help me??
Thanks
paddy
I am trying to run loop injections using TSQ Qantum max ESI for a mass range >1000da and I find poor sensitivity.
I am using 0.1% formic acid+ MeCN (50:50) 0.1ml/min as the mobile phase in the positive ion mode, the samples are about 2mg/ml and I still find it hard to detect mol wt >1000.
Is there anything I can do to improve sensitivity? The manual says, the TSQ is set up for mol wt up to 3000.
Any suggestions which could help me??
Thanks
paddy
