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Signal Noise calculation Chemstation

Posted: Thu Dec 19, 2013 5:20 pm
by cinchocaine
Hello,

when using the Agilent Chemstation software for signal to noise calculations, it apparently uses the formula S/N = Height / Noise.
Besides using 6xSD instead of PtoP, the correct formula should be 2*Height/Noise. Am I right? That's the formula which is given in the EP and USP.
Can anybody clarify, because this halves the S/N ratio in the Chemstation.

Thanks

Re: Signal Noise calculation Chemstation

Posted: Sun Dec 22, 2013 4:13 pm
by ntruong
If my memory doesn't fail me... the range of the noise should be set at 5 x peak (halfwidth) of the peak of interest... then take the s/n value x 2 to get your final result.