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too much noise

Posted: Sat Aug 13, 2005 6:10 am
by moon704520
sth wrong with my varian detrctor 320,the noise was too high about 100mv,days ago the detector was blocked and I fixed it by flow some
hac and pure water through the flow cell ,but after that time ,I find that the noise was too high ,who can tell me what can I do?

detector noise

Posted: Mon Aug 15, 2005 6:26 am
by Chris0000
...clean the flow cell, it seems that there are some waste particles bouncing around....

regards Chris

Posted: Mon Aug 15, 2005 11:01 am
by moon704520
but I do not know how to clean the flow cell ,is there any procedure?can I ultrasonic the flow cell

detector noise

Posted: Mon Aug 15, 2005 3:17 pm
by Chris0000
First remove flow cell

then have a look through the flow path(s)while shaking it slightly

If you can see some dirt or the lenses are not clear, flush it with organic solvent, if this doesn´t help, you can use 1n HNO3

Then flush it with eluent aggain.

regads and good luck
Chris

Too much noise

Posted: Mon Aug 15, 2005 4:34 pm
by skunked_once
Flowcell cleaning procedure:

Flush with methanol followed by water to remove all of the methanol.
Flush with up to 30% nitric acid. Leave the acid in the flowcell for 5-10 minutes then continue flushing.
Flush with water until ALL of the acid is removed then flush again with methanol.
If this doesn't work, you will have to find the detector manual and take apart the flowcell to clean the windows. Be aware that you may need to buy new flowcell windows and gaskets.