Preswollen cellulose

[dc78]

Hello,
i hope i'm not putting this topic in the wrong section. Could you please inform me is there is an alternative product for chromatography separation of hemoglobin a2? I was using deae DE52 pre swollen cellulose which is not anymore commercially available from Whatman. Thank you in advance

[Andy Alpert]

DE52 cellulose is technology that's 50 years old. There have been some advances in hemoglobin analysis and isolation in the interim. Here's an example of the analysis of a hemolyzate that's elevated in hemoglobin A2, using a PolyCAT A column in the cation-exchange mode [key to peaks:
1.353': hemoglobin A1c
1.678': hemoglobin F
2.422': hemoglobin Ao (the big peak)
2.818': hemoglobin A2]