GC-MS Pesticide Analytcsw - Analyte Protectants

[Mr.Brown]

I have some issues with degradation of pesticides

I read some stuff about adding some analyte protectants
like Ethylglycerol, δ-Gulonolactone and Sorbitol

Is there Anybody out there who can give my a hint at what concentration they should be added
or what other compounds could be used.

Trying to do muli-residue analytic using QuEChERs.

Thanks for your help

[bisnettrj2]

Try this paper (sorry about the poor citation):

Anal. Chem. 2005, 77, 8129-8137

Katerina Mastovska, Steven J. Lehotay, and Michelangelo Anastassiades

Combination of Analyte Protectants To Overcome
Matrix Effects in Routine GC Analysis of Pesticide
Residues in Food Matrixes

[shiva_kant]

Dear Mr.Brown

Tri Matrix-matches calibration it may be work for your desired analyte
In case of Multi Residues analysis normally matrix match calibration recommended
But in term of degradation it differ analyte to analyte. Some analyte enhance and some may be suppress.