Chromatography Forum

Hello,

I just started to develop a HPLC Assay method for the determination of Cetrimide and was wondering if someone here knows the pKA-value of Cetrimide? So far I failed in finding a pKa-value anywhere even under its other names such as Alkyltrimethylammonium Bromide.

Many thanks in advance!

M. Planck

The alkyltrimethylammonium part is permanently ionized so to all intents and purposes it doesn't have a pKa. Bromide has a pKa somewhere around -9, so it also is permanently ionized to all intents and purposes.

The alkyltrimethylammonium part is permanently ionized so to all intents and purposes it doesn't have a pKa. Bromide has a pKa somewhere around -9, so it also is permanently ionized to all intents and purposes.

Many thanks for the Information!