Chirobiotic T polar ionic mode

[Mike H.]

I have a general question. I'm trying to resolve a racemic compound using the polar ionic mode. I start to see a hint of separation at 2:1 acid:base ratio, but adjusting this ratio doesn't seem to have an effect on selectivity. I read that for this mode selectivity is governed by acid base ratio so I'm trying to find out why it doesn't seem to affect it here. thanks.

[MestizoJoe]

What is your molecule or what are the ionic functional groups?

You probably did this already but did you try 1:2 instead of 2:1?