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RMS noise of MS

Posted: Mon Jul 08, 2013 8:25 am
by thohry
Hi all,

In the specifications of an LC/MS, It says the signal to noise ratio =3000:1, and Noise =1xRMS. I am not sure what is the meaning of 1 in this case. Anyone can help ?
Thanks.

Re: RMS noise of MS

Posted: Tue Jul 09, 2013 2:35 am
by Don_Hilton
it looks like 1 is a multiplier for the RMS noise.

Re: RMS noise of MS

Posted: Tue Jul 09, 2013 9:52 am
by thohry
it looks like 1 is a multiplier for the RMS noise.
I am not sure.
Possibly it's one time of the peakwidth.

Re: RMS noise of MS

Posted: Tue Jul 09, 2013 11:16 am
by Don_Hilton
If this is not clarified in any of the instrument documentation, I would suggest a call to the instrument manufacturer to clear this up. I don't recognize this as standard notation. The salres or techical support person you call may well need to forward the question to someone in the organization.

Re: RMS noise of MS

Posted: Tue Jul 09, 2013 6:47 pm
by tom jupille
I agree with Don that you should confirm with the manufacturer. I also concur that the "1" is a multiplier. The reason has to do with the various ways of measuring noise.

In most cases, when a signal/noise spec is defined, it's based on "peak to peak" noise (which is just what is sounds like: the difference between the maximum and minimum excursions of the baseline). Peak to peak noise (PtP) is easy to measure manually on a printout (absent the nit-picky issues of how long a stretch of signal to use and, on a chromatogram, where to measure), but is extraordinarily complicated for a data system.

"Root mean square" noise (RMS) is the square root of the sum of the squares of the deviations from the average baseline. As such is it easy for a data system to computer.

The catch is that the relationship between RMS and PtP noise depends on the waveform. I've seen values from 2.8 to 3.3 for sine waves (i.e., PtP = 3.3 x RMS) to 8 for white noise (e.g., http://mdc.custhelp.com/app/answers/det ... peak-noise).

What that "1x" is telling you is simply that the spec is based on RMS, not any version of PtP.

Re: RMS noise of MS

Posted: Thu Jul 11, 2013 11:22 pm
by thohry
Thank you both for the input. I have checked with the vendor, it's simply a multiplier. Don-Hilton is right.